<p>Effectiveness of tonic and burst motor cortex stimulation in chronic neuropathic pain</p>
نویسندگان
چکیده
منابع مشابه
Application of optogenetics-mediated motor cortex stimulation in the treatment of chronic neuropathic pain.
Motor cortex stimulation provides an alternate approach for intractable pain treatment. Optogenetic manipulation can produce gain- or loss-of-function in specific type of cells following light application. This state-of-the-art technology may be used in motor cortex stimulation to produce circuit-specific neuromodulation and regulate neuronal activities in motor cortex, thereby treating pain in...
متن کاملMotor cortex stimulation for central and neuropathic pain: current status.
The idea that central pain syndromes can be treated by manipulation of the motor cortex derives from the landmark observations of Penfield (Lende et al., 1971). While reoperating on patients on whom he had previously resected a portion of the post central gyrus for epilepsy and whose seizures recurred, Penfield observed that stimulation of the corresponding primary motor cortex elicited sensory...
متن کاملMotor cortex electric stimulation for the treatment of neuropathic pain.
OBJECTIVE Motor cortex stimulation (MCS) is considered to be an effective treatment for chronic neuropathic pain. The aim of the present study was to assess the efficacy of MCS for treating neuropathic pain. METHOD 27 patients with chronic neuropathic pain were operated. Electrodes were implanted with the use of an stereotactic frame. Electrophysiological evaluations (motor stimulation and so...
متن کاملTheta Burst Stimulation of the Human Motor Cortex
It has been 30 years since the discovery that repeated electrical stimulation of neural pathways can lead to long-term potentiation in hippocampal slices. With its relevance to processes such as learning and memory, the technique has produced a vast literature on mechanisms of synaptic plasticity in animal models. To date, the most promising method for transferring these methods to humans is re...
متن کاملTreatment of chronic neuropathic pain by motor cortex stimulation: results of a bicentric controlled crossover trial.
BACKGROUND Chronic motor cortex stimulation (MCS) with surgically implanted epidural electrodes has been proposed as a treatment for neuropathic pain refractory compared with medical treatment. However, no prospective controlled trial has been published to provide convincing evidence of MCS analgesic efficacy. OBJECTIVE To compare MCS analgesic efficacy between "ON"- and "OFF"-stimulation con...
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ژورنال
عنوان ژورنال: Journal of Pain Research
سال: 2019
ISSN: 1178-7090
DOI: 10.2147/jpr.s195867